{"id":3514,"date":"2024-03-22T14:59:21","date_gmt":"2024-03-22T13:59:21","guid":{"rendered":"https:\/\/nutriliq.eu\/?p=3514"},"modified":"2024-04-17T12:52:43","modified_gmt":"2024-04-17T11:52:43","slug":"ready-to-take-your-dogs-gut-health-to-the-next-level","status":"publish","type":"post","link":"https:\/\/nutriliq.eu\/en\/solutions\/digestion\/pre-and-probiotics\/ready-to-take-your-dogs-gut-health-to-the-next-level\/","title":{"rendered":"Ready to take your dog&#8217;s gut health to the next level?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"3514\" class=\"elementor elementor-3514\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6d89eab1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6d89eab1\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6c5d94c9\" data-id=\"6c5d94c9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0b6464b elementor-widget elementor-widget-heading\" data-id=\"0b6464b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.19.0 - 07-02-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h1 class=\"elementor-heading-title elementor-size-default\">Ready to take your dog's gut health to the next level? <\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4432208 elementor-widget elementor-widget-text-editor\" data-id=\"4432208\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.19.0 - 07-02-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p><em>In this blog, we&#8217;re exploring the science behind pre-, pro- and postbiotics, along with other key active ingredients and their role in fostering a healthy gut microbiome in dogs. The gut microbiome comprises all microorganisms in the intestines, including bacteria, viruses, fungi and their genetic material, known as microbiota or gut flora. It is vital for various bodily functions such as digestion and immune response, and can be influenced by pre-, pro- and postbiotics, similar to what happens in humans.<\/em><\/p><p><em>As a private-label company, we aim to provide our readers with valuable insights into functional ingredients. Our tailer-made supplements are suitable for dogs of all ages and breeds, aiming to contribute to good overall health.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cbd4956 elementor-widget elementor-widget-heading\" data-id=\"cbd4956\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><b>Nutriliq Product Assortment: Supplement Varieties<\/b><\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-896cdd2 elementor-widget elementor-widget-text-editor\" data-id=\"896cdd2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Nutriliq offers supplements tailored to digestive health, crafted from specific pre- and probiotics along with active ingredients. Beyond just the content, the delivery form of the supplement matters. Ensuring your furry friend correctly and fully absorbs a nutritional supplement into their metabolism might involve testing which form they prefer.<\/p><p>Nutriliq can provide a synbiotic blend in the following forms:<\/p><ul><li>Powder (to mix into regular food)<\/li><li>Chewable treats (chewing gum)<\/li><li>Edible paste<\/li><\/ul><p><br \/>These variations can be supplied in pots of various sizes\/contents. Typically, pots of 200-250g are most commonly requested.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1b3776b elementor-widget elementor-widget-heading\" data-id=\"1b3776b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><b>Prebiotics: Fuel for Good Bacteria<\/b><\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-95b663d elementor-widget elementor-widget-text-editor\" data-id=\"95b663d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Prebiotics are short-chain carbohydrates classified as fibers due to their plant origin and the fact that they are not digested by mammalian enzymes. They are selectively fermented by certain gut microbiota. Consuming prebiotics can significantly modulate the gut microbiota by feeding and increasing specific beneficial bacteria, thereby altering the composition of the microbiota (53, 40).<\/p><p>At Nutriliq, we utilize a blend of FOS, inulin, MOS and GOS, which promote the production of short-chain fatty acids (SCFAs), such as butyrate, propionate and acetate (47, 26). These SCFAs each have their own health benefits for dogs (40).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31b2b54 elementor-widget elementor-widget-heading\" data-id=\"31b2b54\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><b>FOS & inulin<\/b><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5481e97 elementor-widget elementor-widget-text-editor\" data-id=\"5481e97\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Fructo-oligosaccharides (FOS) and inulin are both forms of fructans, consisting of short chains of fructose molecules, often with a glucose molecule at the end (46). Due to the \u03b2-2,1 bonds between the fructose molecules, FOS\/inulin are not easily digested in the upper part of the gastrointestinal tract, allowing them to reach the colon where they are broken down by enzymes produced by certain bacteria (60).<\/p><p>FOS are selectively metabolized by beneficial bacteria (62) and serve as an energy source for specific bacterial species such as <em>Bifidobacterium<\/em>, <em>Lactobacillus<\/em> and <em>Bacteroides<\/em>, thus contributing to a healthy gut flora (81). Research has shown that FOS can effectively alter the gut microbiota, increasing beneficial bacteria and decreasing potentially harmful bacteria such as <em>Clostridium perfringens<\/em> (82, 87). Additionally, scientific evidence has demonstrated that FOS supplementation can improve the immune health of puppies by influencing the production of immunoglobulins in nursing bitches (1).<\/p><p>Nutriliq utilizes dried chicory root, a rich source of inulin. Research by Koz\u0142owska et al. (2015) (47) indicates that inulin supplementation in the diet of dogs has a beneficial effect on the gut microbiome, resulting in an increase in beneficial bacteria such as<em> Bifidobacteria<\/em>. Moreover, inulin promotes gut integrity and has positive effects on nitrogen metabolism in dogs, potentially resulting in reduced unpleasant odor of feces (36, 7).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d73ea7 elementor-widget elementor-widget-heading\" data-id=\"2d73ea7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><b>MOS<\/b><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c60ab82 elementor-widget elementor-widget-text-editor\" data-id=\"c60ab82\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Yeast cell walls, known as mannan-oligosaccharides (MOS), are indigestible carbohydrates that modulate the immune system and influence microbial populations in the gut. MOS acts as a prebiotic by preventing harmful bacteria from adhering to and colonizing the intestinal wall. This property of MOS contributes to maintaining a stable gut environment (83).<\/p><p>Mannans, the primary components of MOS, increase the levels of immunoglobulin A in the blood of dogs. In adult dogs, MOS promotes gut health by increasing the number of lactobacilli and reducing the number of harmful bacteria in the stool (83).<\/p><p>In potential supplements that Nutriliq can formulate, brewer&#8217;s yeast cell walls (100% <em>Saccharomyces cerevisiae<\/em>) are utilized, containing high levels of \u03b2-glucans and mannan-oligosaccharides. It has a positive effect on the microbiome, the immune system and on the binding properties of pathogens and mycotoxins (70). These brewer&#8217;s yeast cell walls exhibit significant prebiotic activity and stimulate the growth of beneficial gut bacteria, as evidenced by an increase in butyrate, lactate, acetate and propionate. Propionate is one of the main energy sources for the intestinal epithelium (26). Therefore, it significantly contributes to the health and protection of the intestine against inflammatory processes (55, 83).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f824575 elementor-widget elementor-widget-heading\" data-id=\"f824575\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><strong>GOS<\/strong><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-212310e elementor-widget elementor-widget-text-editor\" data-id=\"212310e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Galacto-oligosaccharides (GOS) are non-digestible soluble fibers derived from lactose (24). The most common GOS variants, like galactosyllactoses, are naturally found in colostrum and milk from various sources (58).<\/p><p>GOS has a direct effect on the intestinal wall by interacting with epithelial cells, thereby enhancing intestinal integrity and aiding in the defense against inflammatory bowel conditions. Studies suggest that GOS promotes the growth of beneficial bacteria such as Bifidobacteria (17) and Lactobacilli (42). These bacteria produce short-chain fatty acids (15, 50), serving as an energy source (9), inhibiting potential pathogens (86), boosting immune response (69), promoting intestinal mucosa morphology (19), and facilitating mineral absorption in the colon. Consequently, GOS supports carbohydrate fermentation and contributes positively to gut health by enhancing the gut microbiota composition (24).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5459b02 elementor-widget elementor-widget-heading\" data-id=\"5459b02\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Probiotics: Unlocking the Health Benefits of Microorganisms<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-03449e0 elementor-widget elementor-widget-text-editor\" data-id=\"03449e0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Probiotics consist of living colonies of microorganisms that, when added to food, benefit the host by modulating the gut microbiota in favor of non-pathogenic microorganisms (34, 16).<\/p><p>These colonies comprise selected strains of beneficial bacterial species, specifically supported by prebiotics. Prebiotics influence the composition of the gut microbiota by serving as substrates for selective microorganisms. Research indicates that probiotics, as a direct source of beneficial microorganisms, effectively modify the microbial environment of the colon. This is because they can survive passage through the stomach and small intestine of the dog (37, 54, 6).<\/p><p>Probiotics can inhibit the development of pathogenic bacteria by competing for nutrients and binding sites in the intestinal epithelium. They stimulate the host&#8217;s immune system, produce antimicrobial substances, and acidify the intestines through acid production, particularly lactic acid. Additionally, probiotics synthesize vitamins, enzymes and short-chain fatty acids (SCFA), all of which benefit the host (39, 84, 76).<\/p><p>Nutriliq works with three types of probiotics: <em>Bacillus subtilis, Lactobacillus acidophilus<\/em>, and <em>Enterococcus faecium<\/em>. Each of them has slightly different functions.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2f206f8 elementor-widget elementor-widget-heading\" data-id=\"2f206f8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><strong>Bacillus subtilis C-3102<\/strong><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8ac344e elementor-widget elementor-widget-text-editor\" data-id=\"8ac344e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>We utilize a carefully selected <em>Bacillus subtilis<\/em> C-3102 strain, known for promoting a balanced and resilient gut microflora. This strain offers robust protection against pathogens and supports optimal digestion (79). <em>Bacillus<\/em> bacteria are advantageous due to their ability to sporulate, rendering them more resilient to environmental stressors and acidic conditions in the gastrointestinal tract (16). Strain C-3102 demonstrates survivability under diverse temperatures (up to 105\u00b0C), even amidst varying production conditions (79).<\/p><p>Two studies highlight the beneficial effects of <em>B. subtilis<\/em> on fecal quality in dogs, showcasing improvements such as reduced instances of chronic diarrhea (65) and enhancements in fecal texture, odor and composition. Furthermore, its usage correlates with decreased ammonia levels, indicating a reduction in intestinal putrefaction processes (34).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fe228ce elementor-widget elementor-widget-heading\" data-id=\"fe228ce\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><strong>Lactobacillus acidophilus CECT 4529<\/strong><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ab2c3d9 elementor-widget elementor-widget-text-editor\" data-id=\"ab2c3d9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>We also incorporate <em>Lactobacillus acidophilus<\/em> CECT 4529, an anaerobic, non-spore-forming rod-shaped bacterium that produces lactic acid. This contributes to improving stool consistency and fostering a healthy gut flora. Additionally, <em>L. acidophilus<\/em> positively influences local immune defense and shields the intestinal lining from harmful bacteria (33).<\/p><p>Studies indicate that supplementation with<em> L. acidophilus <\/em>leads to increased levels of lactobacilli in the stool, which may help protect dogs against infections caused by <em>Clostridia<\/em>, such as <em>C. difficile<\/em> and <em>C. perfringens<\/em>. Furthermore, it aids in inhibiting the growth of harmful bacteria such as <em>Enterobacteriaceae, Clostridium perfringens, Escherichia coli<\/em> and <em>Enterococcus spp.,<\/em> thereby promoting an improved balance in gut flora (54, 6).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cfb3db8 elementor-widget elementor-widget-heading\" data-id=\"cfb3db8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><strong>Enterococcus faecium NCIMB 10415<\/strong><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-113cc20 elementor-widget elementor-widget-text-editor\" data-id=\"113cc20\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><em>Enterococcus faecium<\/em> is a gram-positive bacterium naturally occurring in the gastrointestinal tract of humans and animals (93, 3), and belongs to the group of lactic acid bacteria. This group, named for the lactic acid they produce during fermentation, includes various beneficial bacterial species (49). <em>E. faecium<\/em> is recognized for its probiotic properties and global use due to its resilience and thriving nature in the intestines (93, 3). Studies have shown that even after supplementation cessation, <em>E. faecium<\/em> can persist in the gut microbiome for up to 19 days (61).<\/p><p>Research indicates that <em>E. faecium<\/em> can enhance dogs&#8217; immune function without adversely affecting their food intake, weight or blood parameters (8). It boosts the production of IgA and IgG antibodies, particularly following vaccinations like those against canine distemper virus (CDV). Additionally, <em>E. faecium <\/em>has been found to alleviate stress-related diarrhea in dogs (73, 20).<\/p><p>Nutriliq incorporates a microbial feed additive composed of dehydrated <em>E. faecium <\/em>cells. Several studies have validated the positive effects of this additive on fecal quality and immune parameters, including IgA concentrations in dogs (31).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0c9f6a7 elementor-widget elementor-widget-heading\" data-id=\"0c9f6a7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Postbiotics: Revealing the Power of Lifeless Microorganisms<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6a63b21 elementor-widget elementor-widget-text-editor\" data-id=\"6a63b21\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Two different definitions exist for postbiotics. <br \/>The first, as established by The International Scientific Association of Probiotics and Prebiotics (ISAPP) and outlined in its report by Salminen et al. (2021) (75), defines postbiotics as a formulation of non-living microorganisms and\/or their components that confer beneficial effects on the host&#8217;s health. Another, more widely accepted definition suggests that postbiotics are non-viable bacterial products or metabolic byproducts of microbiota (43, 68, 85).<\/p><p>Postbiotics emerge from meticulous fermentation processes of raw materials, yielding beneficial metabolites by bacteria and yeasts to bolster health. Postbiotic supplementation, characterized by minimal side effects as it lacks living microorganisms, can aid in resolving disruptions in digestive or gut flora. These disruptions may occur following dietary changes or medication regimens, with the aim of restoring intestinal balance (43, 68, 85, 75).<\/p><p>Nutriliq utilizes a specific type of postbiotics known as Diamond V\u00ae, derived from a fermentation process with <em>Saccharomyces cerevisiae<\/em>. This process yields substances like organic acids, enzymes, short-chain fatty acids (SCFAs) and vitamins, generated by beneficial gut bacteria and yeasts. These substances form valuable metabolites that support gut health (43, 68, 85, 75).<\/p><p>Findings from Lin et al. (2019) (48) reveal the potential benefits of supplementing with a fermentation product of <em>Saccharomyces cerevisiae<\/em> for adult dogs. This supplementation positively influences gut microbiota, enhances immune capacity, and results in reduced presence of potentially pathogenic microorganisms. Moreover, the feed ingredient boasts high palatability and is well-received by dogs (27).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-12f0b3a elementor-widget elementor-widget-heading\" data-id=\"12f0b3a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Other active ingredients<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-061011d elementor-widget elementor-widget-text-editor\" data-id=\"061011d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>In addition to prebiotics, probiotics and postbiotics, there are other beneficial substances that promote optimal digestive system function. Nutriliq incorporates these active ingredients into its supplements specifically aimed at supporting optimal gut health.<\/p><p>Zinc is an essential trace element for various bodily functions in dogs (67). It is absorbed through the intestines but can also be lost through feces, urine, pancreatic juice, hair, skin and nails (11). Nutriliq utilizes <strong>zinc glycinate<\/strong>, a chelated form of organic zinc bound to the amino acid glycine. This form is more bioavailable and better absorbed by the body (51, 52).<\/p><p><strong>Clinoptilolite<\/strong> is utilized for its various beneficial effects, including improving gut flora, enhancing immunity, detoxifying the body by adsorbing toxins such as heavy metals like mercury (4), and preventing diarrhea (4, 14). It is a natural form of zeolite, characterized as a fine-grained, microporous clay mineral (14). Clinoptilolite can enhance stool quality, resulting in improved form, reduced volume and increased consistency (66).<\/p><p><strong><em>Spirulina platensis<\/em><\/strong>, a blue-green microalgae (45), strengthens the immune response and stabilizes the gut microbiota by promoting beneficial bacteria and suppressing harmful bacteria (78, 57, 45, 21). Additionally, it acts as a natural detoxifier, aiding the body in eliminating harmful toxins and benefiting overall health and metabolism (57, 74).<\/p><p><strong><em>Ascophyllum nodosum<\/em><\/strong>, a brown algae from the <em>Fucaceae<\/em> family, is utilized in supplements for its valuable nutritional content, including proteins, minerals, vitamins A, K, C, polyphenols and polysaccharides. It is also rich in fiber (23). Polysaccharides can induce beneficial changes in gut flora (23) and regulate digestive enzymes, which may be interesting for obesity treatment (23, 22). Polysaccharides such as alginates aid the body in detoxifying heavy metals, while fucoidan, ascophyllan and fucoxanthin stimulate the immune response, reduce inflammation, and counteract the development of adipose tissue (92, 38).<\/p><p><strong>Pectins<\/strong> are soluble dietary fibers that can be easily broken down by gut microbiota. This results in the production of short-chain fatty acids that promote a healthy intestinal environment (10, 88, 41, 63). Pectins are also imporant for enhancing gut immunity by promoting the adhesion of beneficial gut bacteria and inhibiting the adhesion of harmful bacteria (91, 64).<\/p><p><strong>L-Glutamine<\/strong> is an alpha-amino acid that is essential for protein synthesis in the body, crucial for cell growth, repair and maintenance (25, 18). During periods of intense stress, the natural production of L-glutamine may decrease, necessitating supplementation. Moreover, L-glutamine energizes intestinal cells, supports the recovery of damaged intestinal tissue, strengthens the intestinal barrier, stimulates an effective immune response, and helps reduce inflammation, such as enteritis (25, 59, 72).<\/p><p><strong>Psyllium husk powder<\/strong> (<em>Plantago psyllium<\/em>) is included in supplements for its high soluble dietary fiber content, which slowly ferments in the colon and exhibits gel-forming properties. It normalizes food passage and promotes water retention in fecal matter, stimulating stool formation and making chronic constipation manageable (88). A study by Alves et al., 2021 (2), demonstrated relief from chronic diarrhea, reduced stool frequency, and improved stool consistency. These positive effects persisted even after two months without continuous psyllium supplementation. All individuals examined showed signs of weight gain, suggesting that psyllium may assist pets struggling with weight gain.<\/p><p><strong>Acacia gum<\/strong> is a soluble secretion from acacia trees and a nutritious source of soluble dietary fibers, primarily composed of complex polysaccharides (71). Research indicates that acacia gum acts as a prebiotic in the gut, promoting the growth and metabolic activity of beneficial bacteria such as <em>Bifidobacterium<\/em> and <em>Lactobacillus<\/em>. These bacteria ferment prebiotic compounds like fructo-oligosaccharides (FOS), yielding beneficial metabolites such as short-chain fatty acids. This leads to improved gut health by lowering pH levels and increasing energy supply to intestinal cells (32).<\/p><p><strong>Quercetin<\/strong>, a flavonoid with antioxidant properties, provides protection against cell damage and DNA injury (12). It is known for its antihistamine effects, allowing it to regulate histamine levels. This can aid in reducing itching and inflammation in dogs with allergies (5, 28, 90, 35, 44, 80), as well as in dogs with chronic inflammatory digestive diseases (29).<\/p><p><strong>Colostrum<\/strong> contains immune-enhancing components such as immunoglobulins, which strengthen the immune response at both mucosal and systemic levels (13, 30, 56, 78). This can help reduce allergic reactions that cause itching. The bioactive compounds such as probiotics and growth factors promote digestion and aid in maintaining balanced intestinal function (13, 30, 56, 78).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-85a0892 elementor-widget elementor-widget-heading\" data-id=\"85a0892\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Reference list<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0d54aba elementor-widget elementor-widget-text-editor\" data-id=\"0d54aba\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ol>\n<li>Adogony, V., Respondek, F., Biourge, V., Rudeaux, F., Delaval, J., Bind, J-L., Salmon, H. (2007). Effects of dietary scFOS on immunoglobulins in colostrums and milk of bitches. <em>J Anim Physiol Anim Nutr, 91<\/em>: 169\u2013174. <a href=\"https:\/\/doi.org\/10.1111\/j.1439-0396.2007.00688.x\">https:\/\/doi.org\/10.1111\/j.1439-0396.2007.00688.x<\/a><\/li>\n<li>Alves, J.C., Santos, A., Jorge, P., Pit\u00e3es, A. (2021). The use of soluble fibre for the management of chronic idiopathic large bowel diarrhoea in police working dogs. <em>BMC Veterinary Research, 17<\/em> (1): 100. <a href=\"https:\/\/doi.org\/10.1186\/s12917-021-02809-w\">https:\/\/doi.org\/10.1186\/s12917-021-02809-w<\/a><\/li>\n<li>Ara\u00fajo, T.F., Ferreira, C.L.L.F. (2013). The Genus Enterococcus as Probiotic. <em>Brazilian Archives of Biology and Technology, 56<\/em> (3): 457\u2013466. <a href=\"https:\/\/doi.org\/10.1590\/S1516-89132013000300014\">https:\/\/doi.org\/10.1590\/S1516-89132013000300014<\/a><\/li>\n<li>Ariton, A.M., Neculai-Valeanu, A.S., S\u0103nduleanu, C., Crivei, I.C., Postolache, A.N., Porosnicu, I., M\u0103descu, B.M., Ungureanu, E., Trinc\u0103, L.C. (2022). Applications of Clinoptilolite in Veterinary Medicine and Animal Husbandry. <em>Scientific Papers Journal, 65<\/em> (4). <a href=\"https:\/\/www.researchgate.net\/publication\/369109310\">https:\/\/www.researchgate.net\/publication\/369109310<\/a><\/li>\n<li>Atuahene, D., Costale, A., Martello, E., Mannelli, A., Radice, E., Ribaldone, D.G., Chiofalo, B., Stefanon, B., Meineri, G. (2023). A Supplement with Bromelain, <em>Lentinula edodes<\/em>, and Quercetin: Antioxidant Capacity and Effects on Morphofunctional and Fecal Parameters (Calprotectin, Cortisol, and Intestinal Fermentation Products) in Kennel Dogs. <em>Veterinary Sciences, 10 <\/em>(8): 486. <a href=\"https:\/\/doi.org\/10.3390\/vetsci10080486\">https:\/\/doi.org\/10.3390\/vetsci10080486<\/a><\/li>\n<li>Baillon, M.L., Marshall-Jones, Z.V., Butterwick, R.F. (2004). Effects of probiotic Lactobacillus acidophilus strain DSM13241 in healthy adult dogs. <em>American Journal of Veterinary Research, 65 <\/em>(3): 338\u2013343. <a href=\"https:\/\/doi.org\/10.2460\/ajvr.2004.65.338\">https:\/\/doi.org\/10.2460\/ajvr.2004.65.338<\/a><\/li>\n<li>Barko, P.C., McMichael, M.A., Swanson, K.S., Williams, D.A. (2018). 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Editorial Special Issue \u201cEnterococci for Probiotic Use: Safety and Risk\u201d: Editorial. <em>Microorganisms, 10<\/em>: 604.&nbsp;<a href=\"https:\/\/doi.org\/10.3390\/microorganisms10030604\" style=\"background-color: rgb(255, 255, 255); font-family: var( --e-global-typography-accent-font-family ), Sans-serif; font-size: var( --e-global-typography-accent-font-size ); font-weight: var( --e-global-typography-accent-font-weight );\">https:\/\/doi.org\/10.3390\/microorganisms10030604<\/a><\/li><\/ol>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Ready to take your dog&#8217;s gut health to the next level? In this blog, we&#8217;re exploring the science behind pre-, pro- and postbiotics, along with other key active ingredients and their role in fostering a healthy gut microbiome in dogs. The gut microbiome comprises all microorganisms in the intestines, including bacteria, viruses, fungi and their [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[101,1,124],"tags":[123,125,121,122],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Ready to take your dog&#039;s gut health to the next level? | Nutriliq<\/title>\n<meta name=\"description\" content=\"Explore the science behind pre-, pro- and postbiotics, along with other key active ingredients and their role in fostering a healthy gut microbiome in dogs.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nutriliq.eu\/en\/solutions\/digestion\/pre-and-probiotics\/ready-to-take-your-dogs-gut-health-to-the-next-level\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ready to take your dog&#039;s gut health to the next level? 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